Neutralizing Monoclonal Antibodies to Striped Jack Nervous Necrosis Virus (SJNNV).
نویسندگان
چکیده
منابع مشابه
Mapping a neutralizing epitope on the coat protein of striped jack nervous necrosis virus.
Striped jack nervous necrosis virus (SJNNV), a fish nodavirus, is the causative agent of viral nervous necrosis in marine fishes. The fish nodaviruses are divided into four different genotypes based on the nucleotide sequence of the coat protein gene. In the present study, partial coat protein genes of fish nodaviruses were expressed. This allowed the serological relationship among the differen...
متن کاملSequence of the non-structural protein gene encoded by RNA1 of striped jack nervous necrosis virus.
Striped jack nervous necrosis virus (SJNNV), the causative agent of viral nervous necrosis in marine fish, is a member of the family Nodaviridae whose genome consists of two positive-sense RNA molecules encapsidated in a single virion. In this study, the nucleotide sequence of SJNNV RNA1 was determined. The SJNNV RNA1 was 3081 bases long and contained a single ORF encoding 983 aa of approximate...
متن کاملIdentification of host-specificity determinants in betanodaviruses by using reassortants between striped jack nervous necrosis virus and sevenband grouper nervous necrosis virus.
Betanodaviruses, the causal agents of viral nervous necrosis in marine fish, have bipartite positive-sense RNAs as genomes. The larger genomic segment, RNA1 (3.1 kb), encodes an RNA-dependent RNA polymerase, and the smaller genomic segment, RNA2 (1.4 kb), codes for the coat protein. Betanodaviruses have marked host specificity, although the primary structures of the viral RNAs and encoded prote...
متن کاملNeutralizing monoclonal antibodies recognize antigenic variants among isolates of infectious hematopoietic necrosis virus
Neutralizing monoclonal antibodies were developed against strains of infectious hematopoietic necrosis virus (IHNV) from steelhead trout Salmo gajrdneri in the Deschutes River of Oregon, chinook salmon Oncorhynchus tshawytscha in the Sacramento h v e r of California, and rainbow trout Salmo gairdneri reared in the Hagerman Valley of Idaho. USA. These antibodies were tested for neutralization of...
متن کاملNear-Complete Genome Sequence of a Fish Nervous Necrosis Virus Isolated from a Clinical Disease Outbreak in Farm-Reared Bream Sparus aurata in Spain
Sparus aurata larvae infected by viral nervous necrosis were collected from an aquaculture fish farm. The isolated viral genome, composed of two segments (RNA1 and RNA2), was sequenced and analyzed comparatively. Phylogenetic tree analyses revealed that the isolated strain is a reassortant, exhibiting a red-spotted grouper nervous necrosis virus (RGNNV)-type RNA1 and a striped jack nervous necr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Fish Pathology
سال: 1995
ISSN: 0388-788X,1881-7335
DOI: 10.3147/jsfp.30.111